Searchable abstracts of presentations at key conferences in endocrinology

ea0032p176 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2013

Long QT interval in Turner syndrome: a high prevalence of LQTS gene mutations

Trolle Christian , Mortensen Kristian Havmand , Pedersen Lisbeth Norum , Jensen Henrik Kjaerulf , Andersen Niels Holmark , Gravholt Claus Hojbjerg

Objective: QT interval prolongation of unknown aetiology is common in Turner syndrome (TS). This study set out to explore the presence of known pathogenic long QT (LQT) mutations in TS and to examine the corrected QT interval (QTc) over time and relate the findings to the TS phenotype.Methods: Adult females with TS (n=102) were examined thrice with a mean follow-up of 4.7±0.5 years, and 68 age-matched healthy controls were examined once. QT...